Naz, Farah published the artcileIn vivo hepatoprotective and in vitro antimicrobial potential of Ceasalpinia bonduc (Linn): pharmacological correlation with identified phytochemicals, Safety of Isobutyl palmitate, the publication is Pakistan Journal of Pharmaceutical Sciences (2021), 34(Suppl.2), 809-817, database is CAplus.
The in vivo hepatoprotective potential of methanolic extract of Ceasalpinia bonduc (CBLM) has been explored against carbon tetrachloride (CCl4) induced acute liver injury in rats. Treatment of plant extract on CCl4 intoxicated liver significantly reduced the hepatoxicity, along with serum enzymes GPT and GOT. To explore the chem. constituents from CBLM extract, it was fractionated into non-polar to moderately polar fractions (CBLM-H, CBLM-HEt, CBLM-Et, CBLM-EtM, CBLM-M) and subjected to GC/GC-MS anal. Altogether twenty seven (~71%) phytochems. were identified from different fractions by using Electronic Mass Spectral Library GC-MS (NIST 20). Out of which twenty one are first time reported from Ceasalpinia bonduc, fourteen from genus Caesalpinia and ten from family Fabaceae. The identified phytochems. 2-ethyl-2-hydroxy-1,3-dimethylcyclopentanecarboxylic acid, Et ester (21) and 1,3,5-triazine-2,4-diamine,6-hydroxy-N,N-dicyclohexyl (23) are first time identified as plant metabolites. To explore the antimicrobial potential four strains of Gram-pos. and eight strains of Gram-neg. bacteria were used along with pure cultures of five saprophytic fungus (molds) and two strains of yeast were utilized. CBLM-H and CBLMHEt were exhibited praiseworthy antimicrobial potential. CBLM-H showed complete growth inhibition of P. mirabilis and V. cholerae at the concentration of 0.1μg/mL while CBLM-HEt at 0.05μg/mL halted the growth of S. aureus.
Pakistan Journal of Pharmaceutical Sciences published new progress about 110-34-9. 110-34-9 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ester, name is Isobutyl palmitate, and the molecular formula is C20H40O2, Safety of Isobutyl palmitate.
Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics