Nakano, Ayako’s team published research in Organic Letters in 8 | CAS: 106391-88-2

Organic Letters published new progress about 106391-88-2. 106391-88-2 belongs to esters-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Amide,Aldehyde, name is (R)-tert-Butyl (3-methyl-1-oxobutan-2-yl)carbamate, and the molecular formula is C10H19NO3, Product Details of C10H19NO3.

Nakano, Ayako published the artcileβ-Isocupreidine-Catalyzed Baylis-Hillman Reaction of Chiral N-Boc-α-Amino Aldehydes, Product Details of C10H19NO3, the publication is Organic Letters (2006), 8(23), 5357-5360, database is CAplus and MEDLINE.

β-Isocupreidine (β-ICD)-catalyzed Baylis-Hillman reaction of chiral N-Boc-α-amino aldehydes BocNR1CHR2CHO [Boc = Me3CO2C; R1 = H, R2 = Me, Me2CH, Me2CHCH2; R1R2 = (CH2)3, CMe2OCH2] and 1,1,1,3,3,3-hexafluoroisopropyl acrylate (HFIPA) takes place without racemization and exhibits the match-mismatch relationship between the substrate and the catalyst. In the case of acyclic amino aldehydes, L-substrates show excellent syn selectivity and high reactivity in contrast to D-substrates. On the other hand, in the case of cyclic amino aldehydes, D-substrates rather than L-substrates show excellent anti selectivity and high reactivity. The Baylis-Hillman adducts obtained were transesterified and further converted into carboxyvinyl-substituted oxazolidines and (hydroxy)(methylene)pyrrolidinones.

Organic Letters published new progress about 106391-88-2. 106391-88-2 belongs to esters-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Amide,Aldehyde, name is (R)-tert-Butyl (3-methyl-1-oxobutan-2-yl)carbamate, and the molecular formula is C10H19NO3, Product Details of C10H19NO3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics