Han, Li-Jun published the artcilePalladium-Catalyzed Methoxycarbonylation of 1,3-Butadiene to Methyl-3-Pentenoate: Introduction of a Continuous Process, Recommanded Product: Dimethyl adipate, the publication is Journal of Catalysis (2021), 283-290, database is CAplus.
The base-assisted Pd(cod)Cl2/xantphos-catalyzed methoxycarbonylation of 1,3-butadiene (BD) to methyl-3-pentenoate (MP) was explored. Mechanistic studies suggested excessive xantphos (beyond an equimolar amount per Pd) as well as its substitute, pyridines of proper steric and electronic functionality, do participate catalytic cycle and significantly reduce activation energy by accelerating rate-limiting methanolysis step. As thus, all reaction parameters, especially solvents, were optimized based on Pd(cod)Cl2/Xantphos/4-hexylpyridine catalytic system, enabling construction of a continuous process. Systematic optimization demonstrated that a yield of 82% of MP with a purity of 99.8% could be reached under steady-state operation.
Journal of Catalysis published new progress about 627-93-0. 627-93-0 belongs to esters-buliding-blocks, auxiliary class Ploymers, name is Dimethyl adipate, and the molecular formula is C8H14O4, Recommanded Product: Dimethyl adipate.
Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics