Guldberg, T. S. published the artcileAnalysis of synthetic antioxidants in salmon silage using QuEChERS extraction method followed by determination by LC-MS/MS; a single-laboratory validation study, SDS of cas: 121-79-9, the publication is Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences (2021), 122715, database is CAplus and MEDLINE.
A new method was developed and inhouse validated to determined ethoxyquin (EQ), butylated hydroxyanisole (BHA) and Pr gallate (PG) in fish silage and fish oil used for production of animal feed. Sample pre-treatment comprises use of QuEChERS (quick, easy, cheap, effective, rugged and safe) extraction and gives extracts for liquid chromatog.-triple quadrupole mass spectrometry anal. without matrix interferences. The results allow quantification of the antioxidants in all matrixes by using deuterated internal standards and calibration curves made in solvent, as well as establishing low detection limits (0.012-0.015 mg/kg) and quantification limits (0.040-0.050 mg/kg) needed regarding the recent suspension of EQ as feed additive within the European Union. The proposed method was validated in terms of linearity, accuracy (relative error, ±1.4%), precision (RSD, â?.7%) and recovery (matrix effect, 97-101%) where all the parameters show acceptable results according to recognized guidelines (including EuraChem) within method validation. Combined expanded measurement uncertainty was estimated with a coverage factor of 2 by including all contributors to anal. variation, showing results of ±15% or better. The combined QuEChERS and LC-MS/MS method was successfully applied to salmon silage samples and their corresponding aqueous and oil fractions.
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C10H12O5, SDS of cas: 121-79-9.
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