Gong, Xia’s team published research in Biosensors & Bioelectronics in 87 | CAS: 3052-61-7

Biosensors & Bioelectronics published new progress about 3052-61-7. 3052-61-7 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Amide, name is Benzyl diethylcarbamodithioate, and the molecular formula is C12H17NS2, COA of Formula: C12H17NS2.

Gong, Xia published the artcileSynthesis of adenosine-imprinted microspheres for the recognition of ADP-ribosylated proteins, COA of Formula: C12H17NS2, the publication is Biosensors & Bioelectronics (2017), 858-864, database is CAplus and MEDLINE.

Core-shell structural adenosine-imprinted microspheres were prepared via a two-step procedure. Polystyrene core particles (CP) were firstly prepared via a reversible addition-fragmentation chain transfer (RAFT) polymerization leaving the iniferter on the surface of the cores, then a molecularly imprinted polymer (MIP) shell was synthesized on the surface of the cores by using acrylamide (AAm) as the functional monomer and ethylene glycol dimethacrylate (EGDMA) as the cross-linker. The formation and growth of the MIP layer were seen dependent on the initiator (AIBN), AAm and the polymerization time used within the polymerization SEM/TEM images showed that the dimensions of the cores and shells were 2μM and 44 nm, resp. The MIP microspheres exhibited a fast rebinding rate within 2 h and a maximum adsorption capacity of 177μg per g for adenosine. The adsorption fitted a Langmuir-Freundlich (LF) isotherm model with a KLF value of 41 mL/μg and a qm value of 177μg/g for the MIP microspheres. The values were larger than those for a non-molecularly imprinted polymer (NIP) particles (5 mL/μg and 88μg/g) indicating a better adsorption ability towards adenosine. The MIP microspheres showed a good selectivity for adenosine with a higher adsorption (683 nmol/g) for adenosine than that (91 nmol/g, 24 nmol/g and 54 nmol/g) for guanosine, cytidine and uridine resp. Further experiment proved that the adenosine-imprinted polymer microspheres also had a good selectivity for ADP-ribosylated proteins that the MIP could extract the ADP-ribosylated proteins from the cell extract samples.

Biosensors & Bioelectronics published new progress about 3052-61-7. 3052-61-7 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Amide, name is Benzyl diethylcarbamodithioate, and the molecular formula is C12H17NS2, COA of Formula: C12H17NS2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics