Guo, Wei published the artcileBase-Promoted Three-Component Cyclization and Coupling Strategy for the Synthesis of Substituted 3-Aryl-5-thio-1,3,4-thiadiazole-2-thiones, Safety of Dimethyl itaconate, the publication is Asian Journal of Organic Chemistry (2022), 11(3), e202100745, database is CAplus.
An effective base-promoted cyclization and coupling strategy for the construction of substituted 3-aryl-5-thio-1,3,4-thiadiazole-2-thiones I [R1 = Ph, 4-MeC6H4, 4-ClC6H4, etc.; R2 = C(O)OMe, C(O)CH2CH(Me)2, C(O)N(Me)2, etc.] from phenylhydrazines, olefins and CS2 was developed through employing CS2 as a sulfur feedstock. The reaction proceeded under mild reaction conditions in the absence of any external catalysts, transition metals and ligands. The one-step three-component procedure also showed the merits of simple operation, using available starting materials, wide substrate scopes, and high atom and step economy. This reaction provided facile access to substituted 3-aryl-5-thio-1,3,4-thiadiazole-2-thiones I, which could be used in the field of drug research.
Asian Journal of Organic Chemistry published new progress about 617-52-7. 617-52-7 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Aliphatic hydrocarbon chain,Ester, name is Dimethyl itaconate, and the molecular formula is C7H10O4, Safety of Dimethyl itaconate.
Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics