Takemoto, Kohei published the artcileSite-selective esterifications of polyol β-hydroxyamides and applications to serine-selective glycopeptide modifications, Related Products of esters-buliding-blocks, the main research area is glycopeptide synthesis serine sugar steric hindrance; hydroxyamide polyol esterification hydroxyl group acylation.
The site-selective acylations of β-hydroxyamides in the presence of other hydroxyl groups are described. Central to the success of this modification is the metal-template-driven acylation using pyridine ketoxime esters as acylating reagents in combination with CuOTf. This strategy enables β-hydroxyl groups to be site-selectively acylated in various derivatives, including sterically hindered secondary β-alc. The utility of this methodol. is showcased by the serine-selective modification of a glycopeptide with unprotected sugar.
Organic Letters published new progress about Acylation. 5405-41-4 belongs to class esters-buliding-blocks, name is Ethyl 3-hydroxybutanoate, and the molecular formula is C6H12O3, Related Products of esters-buliding-blocks.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics