Seghezzo, Sara P. published the artcileExtended Follow-up After Hematopoietic Cell Transplantation for IκBα Deficiency with Disseminated Mycobacterium avium Infection, SDS of cas: 55981-09-4, the main research area is Mycobacterium hematopoietic cell transplantation IkB alpha; IκBα; Mycobacterium avium; NFKBIA; hematopoietic cell transplantation; immunodeficiency; recurrent infection.
This article relates to extended follow-up after hematopoietic cell transplantation for IκBα deficiency with disseminated Mycobacterium avium infection. Pre-transplant imaging revealed enlarged retroperitoneal lymph nodes that were pos. for MAC on biopsy. This infection was controlled but not resolved after 5 mo of a 5-drug regimen that included clofazimine, azithromycin, amikacin, ethambutol, and rifampin. The patient developed grade 2 skin graft vs. host disease (GVHD) starting day + 90, which responded to steroids and sirolimus. Addnl. post-transplant complications included a Pseudomonas putida central line infection and disseminated reactivation of vaccine-strain varicella following discontinuation of acyclovir 6 mo post-transplant. Reconstitution of the adaptive immune system was lifesaving for our patient and allowed for resolution of his MAC infection; however, he remains vulnerable to recurrent. Sinopulmonary infections.
Journal of Clinical Immunology published new progress about Apoptosis. 55981-09-4 belongs to class esters-buliding-blocks, name is 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate, and the molecular formula is C12H9N3O5S, SDS of cas: 55981-09-4.
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