Beckwith, Athelstan L. J. published the artcileReactions of methyl-substituted 5-hexenyl and 4-pentenyl radicals, Category: esters-buliding-blocks, the main research area is hexenyl radical cyclization kinetics; methyl group hexenyl cyclization; pentenyl radical cyclization kinetics.
Relative and absolute kinetic data were determined for cyclization of Me-substituted 5-hexenyl radicals: 2-, 3- and 4-Me- and 2,2-, 3,3- and 4,4-diMe-substituted radicals, generated by interaction of Bu3SnH with the corresponding bromides. Each radical undergoes regiospecific or highly regioselective 1,5-cyclization more rapidly than the unsubstituted radical. The rate enhancements, which arise mainly from lowering of the activation energy, can be rationalized in terms of the gem-di-Me effect. 1,5-Cyclizations of monosubstituted species are stereoselective: 2- and 4-methyl-5-hexenyl radicals give mainly trans products, whereas 3-methyl-4-hexenyl radical gives mainly the cis. This behavior reflects the effect of the substituent on the stabilities of cyclic transition complexes in chair-like conformations. Cyclization of 2,2- or 3,3-dimethyl-4-pentenyl radical could not be detected.
Australian Journal of Chemistry published new progress about Cyclization. 86549-27-1 belongs to class esters-buliding-blocks, name is Ethyl 2,2-dimethylpent-4-enoate, and the molecular formula is C9H16O2, Category: esters-buliding-blocks.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics