Li, Chunching published the artcileBuoyancy-Driven Gradients for Biomaterial Fabrication and Tissue Engineering, Synthetic Route of 142-90-5, the main research area is osteochondral tissue engineering biomaterial polymer hydrogel buoyancy; biomaterials; buoyancy; gradients; osteochondral; tissue engineering.
The controlled fabrication of gradient materials is becoming increasingly important as the next generation of tissue engineering seeks to produce inhomogeneous constructs with physiol. complexity. Current strategies for fabricating gradient materials can require highly specialized materials or equipment and cannot be generally applied to the wide range of systems used for tissue engineering. Here, the fundamental phys. principle of buoyancy is exploited as a generalized approach for generating materials bearing well-defined compositional, mech., or biochem. gradients. Gradient formation is demonstrated across a range of different materials (e.g., polymers and hydrogels) and cargos (e.g., liposomes, nanoparticles, extracellular vesicles, macromols., and small mols.). As well as providing versatility, this buoyancy-driven gradient approach also offers speed (<1 min) and simplicity (a single injection) using standard laboratory apparatus Moreover, this technique is readily applied to a major target in complex tissue engineering: the osteochondral interface. A bone morphogenetic protein 2 gradient, presented across a gelatin methacryloyl hydrogel laden with human mesenchymal stem cells, is used to locally stimulate osteogenesis and mineralization in order to produce integrated osteochondral tissue constructs. The versatility and accessibility of this fabrication platform should ensure widespread applicability and provide opportunities to generate other gradient materials or interfacial tissues. Advanced Materials (Weinheim, Germany) published new progress about Biomineralization. 142-90-5 belongs to class esters-buliding-blocks, name is Dodecyl 2-methylacrylate, and the molecular formula is C16H30O2, Synthetic Route of 142-90-5.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics