Chen, Ruyu published the artcileSynthesis of N-(methoxycarbonyl or isopropylcarbamoylmethoxyphosphonyl)-α-amino acid ester and their stereomers, Safety of Methyl 2-aminopentanoate hydrochloride, the main research area is amino acid phosphonyl preparation.
N-(methoxycarbonylmethoxyphosphonyl)-α-amino acid esters (I) were synthesized via the reaction of MeO2CP(O)ClOMe with amino acid ester hydrochlorides in the presence of a base. Compound I was aminated to yield N-(isopropylcarbamoylmethoxyphosphonyl)-α-amino acid esters (II). With l-amino acids as starting materials, the isomers of products I and II were separated and their configurations were confirmed by single crystal X-ray diffraction of II.
Science in China, Series B: Chemistry published new progress about Amino acids Role: SPN (Synthetic Preparation), PREP (Preparation) (phosphonyl). 10047-10-6 belongs to class esters-buliding-blocks, name is Methyl 2-aminopentanoate hydrochloride, and the molecular formula is C6H14ClNO2, Safety of Methyl 2-aminopentanoate hydrochloride.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics