Liu, Xu published the artcileRing-contraction of hantzsch esters and their derivatives to pyrroles via electrochemical extrusion of ethyl acetate out of aromatic rings, Application In Synthesis of 140-11-4, the main research area is Hantzsch ester electrochem ring contraction; pyrrolyl ester preparation.
Electrochem. ring-contraction of HEs and theirs pyridine derivatives was developed to obtain polysubstituted pyrroles. This process provided an orthogonal utilization of Hantzsch esters for the well-documented application as side chain or hydrogen donors. The formal transformation showed an extrusion of Et acetate out of the pyridine ring in a single step. In addition to the novel transformation, this study also discovered the Lewis acid’s intermol. control of regioselectivity during an intramol. electrochem. process. The reaction provided a number of polysubstituted pyrroles that have never been accessed, including pharmaceutical intermediates and photoswitches. An unusual 4-electron continuous reduction drives the unprecedented anionic dearomatization/ring-contraction/rearomatization pathway.
Green Chemistry published new progress about Esters Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (Hantzsch). 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Application In Synthesis of 140-11-4.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics