Konno, Tsutomu published the artcileSynthesis and application of α-trifluoromethylated aldehydes, Formula: C9H16O4, the main research area is trifluoromethylated aldehyde preparation; nucleophilic addition stereoselective trifluoromethylated aldehyde; Pummerer rearrangement; oxidative cleavage diol stereoselective.
Two methods for the synthesis of α-trifluoromethylated aldehydes are described. One is a synthetic method via Pummerer rearrangement followed by the hydrolysis under the weakly basic condition, giving the racemic aldehyde. The other is via the oxidative cleavage of the corresponding diol under the acidic condition, affording the optically active compound for the first time. Furthermore, both aldehydes underwent the reaction with some nucleophiles in good yields.
Tetrahedron published new progress about Nucleophilic addition reaction, stereoselective. 61675-94-3 belongs to class esters-buliding-blocks, name is Ethyl 2-((tetrahydro-2H-pyran-2-yl)oxy)acetate, and the molecular formula is C9H16O4, Formula: C9H16O4.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics