McCourt, Ruairi O. published the artcileA Sequential Acyl Thiol-Ene and Thiolactonization Approach for the Synthesis of δ-Thiolactones, Quality Control of 539-88-8, the main research area is thiolactone synthesis unsaturated ester acyl thiol ene Steglich thiolactonization.
A novel strategy for the synthesis of δ-thiolactones from inexpensive and readily available γ-unsaturated esters has been developed. This strategy incorporates a radical acyl thiol-ene reaction as the key C-S bond forming step. Cyclization is achieved via a Steglich-type thiolactonization of 5-mercaptopentanoic acids. We report the facile and scalable synthesis of δ-thiolactones in moderate to good yield under mild reaction conditions with tolerance for a range of functional groups.
Organic Letters published new progress about Johnson-Claisen rearrangement (for synthesis of γ-unsaturated esters). 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, Quality Control of 539-88-8.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics