Synthesis of substituted imid(thi)azolidines by [3+2] cycloaddition of aziridines with nitriles(isothiocyanates) via visible light photocatalysis was written by Ye, Qianwen;Xu, Xiaoliang;Cheng, Dongping;Guan, Baochuan;Ye, Hongfeng;Li, Xiaonian. And the article was included in ARKIVOC (Gainesville, FL, United States) in 2017.Safety of Isopropylisothiocyanate The following contents are mentioned in the article:
The [3+2] cycloaddition reaction of aziridines with nitriles (isothiocyanates) has been developed using visible light photocatalysis. Two types of five-membered heterocyclic compounds, imidazolidines and thiazolidines, were synthesized in mild conditions. An oxidative quenching cycle mechanism is probably involved. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Safety of Isopropylisothiocyanate).
Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Safety of Isopropylisothiocyanate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics