RAFT-polymerized poly(hexafluoroisopropyl methacrylate)s as precursors for functional water-soluble polymers was written by Nuhn, Lutz;Overhoff, Iris;Sperner, Marcel;Kaltenberg, Katrin;Zentel, Rudolf. And the article was included in Polymer Chemistry in 2014.Quality Control of 1,1,1,3,3,3-Hexafluoroisopropylmethacrylate The following contents are mentioned in the article:
Post-polymerization modification of well-defined precursor polymers is a versatile tool to obtain multifunctional water-soluble polymers that cannot be synthesized by common polymerization techniques. For the first time, 1,1,1,3,3,3-hexafluoroisopropyl methacrylate (HFIPMA) based homo and block copolymers were synthesized via RAFT polymerization to provide precise precursors for the post-polymerization modification of the 1,1,1,3,3,3-hexafluoroisopropyl ester side chains with water-soluble amines (methoxy tri(ethylene glycol)amine, 2-hydroxypropylamine and 3-(dimethylamino)-1-propylamine). Sequential aminolysis using Oregon Green cadaverine first, followed by 2-hydroxypropylamine enables access to dye-labeled poly(2-hydroxypropyl methacrylamide) and aminolysis with 3-(dimethylamino)-1-propylamine provides homo and block co-catiomers that complex pDNA in PBS. To this respect, poly(1,1,1,3,3,3-hexafluoroisopropyl methacrylate)s P(HFIPMA)s as precursor polymers may become an alternative route for the synthesis of multifunctional water-soluble polymers for advanced applications. This study involved multiple reactions and reactants, such as 1,1,1,3,3,3-Hexafluoroisopropylmethacrylate (cas: 3063-94-3Quality Control of 1,1,1,3,3,3-Hexafluoroisopropylmethacrylate).
1,1,1,3,3,3-Hexafluoroisopropylmethacrylate (cas: 3063-94-3) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Quality Control of 1,1,1,3,3,3-Hexafluoroisopropylmethacrylate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics