Jen, Timothy published the artcileAdrenergic agents. 8. Synthesis and β-adrenergic agonist activity of some 3-tert-butylamino-2-(substituted phenyl)-1-propanols, Recommanded Product: Methyl 2-(3-formyl-4-hydroxyphenyl)acetate, the publication is Journal of Medicinal Chemistry (1977), 20(10), 1263-8, database is CAplus and MEDLINE.
Title compounds I-HCl [61874-10-0], II hemifumarate [63857-50-1], III-HCl [61874-03-1], IV hemifumarate [63857-52-3], and V-2HCl [61873-98-1] were prepared and tested in the spontaneously contracted guinea pig tracheal chain preparation and the spontaneously beating guinea pig right atria. The title phenylpropanolamine compounds were less potent in the tracheal chain preparation test than the analogous phenylethanolamine compounds The selectivity for tracheal vs. cardiac muscle of the phenylpropanolamines is greater than for isoproterenol, but less than for the phenylethanolamine analogs, in most cases. Structure-activity relations are discussed.
Journal of Medicinal Chemistry published new progress about 61874-04-2. 61874-04-2 belongs to esters-buliding-blocks, auxiliary class Benzene,Phenol,Ester,Aldehyde, name is Methyl 2-(3-formyl-4-hydroxyphenyl)acetate, and the molecular formula is C10H10O4, Recommanded Product: Methyl 2-(3-formyl-4-hydroxyphenyl)acetate.
Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics