Al-Trawneh, Salah A. published the artcileA new efficient route to 7-aryl-6-fluoro-8-nitroquinolones as potent antibacterial agents, Product Details of C7H13NO2, the publication is European Journal of Medicinal Chemistry (2014), 364-367, database is CAplus and MEDLINE.
A series of 7-aryl-6-fluoro-8-nitroquinolones were synthesized through a novel, simple and clean synthetic procedure, through a Suzuki-Miyaura reaction. The target compounds were evaluated in vitro for their antimicrobial properties against bacterial and fungal strains. All of them showed antibacterial activity higher than the activity of ciprofloxacin, both towards Gram pos. Bacillus subtilis and Staphylococcus aureus, and Gram neg. Haemophilus influenzae strains. Compound 1-Cyclopropyl-6-fluoro-7-(4-methoxy-3,5-dimethylphenyl)8-nitro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, containing the trisubstituted 7-aryl moiety, emerged as the most active quinolone derivative with MIC values ranging from 0.00007 μg/mL to 0.015 μg/mL.
European Journal of Medicinal Chemistry published new progress about 924-99-2. 924-99-2 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Amine,Aliphatic hydrocarbon chain,Ester, name is Ethyl 3-(dimethylamino)acrylate, and the molecular formula is C7H13NO2, Product Details of C7H13NO2.
Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics