Al-Huniti, Mohammed H. published the artcileHeterocycles [h]fused onto 4-oxoquinoline-3-carboxylic acid, Part IV. Convenient synthesis of substituted hexahydro[1,4]thiazepino[2,3-h]quinoline-9-carboxylic acid and its tetrahydroquino[7,8-b]benzothiazepine homolog, Computed Properties of 924-99-2, the publication is Molecules (2007), 12(8), 1558-1568, database is CAplus and MEDLINE.
Substituted [1,4]thiazepino[2,3-h]quinolinecarboxylate I is prepared by PPA-catalyzed thermal lactamization of the resp. 8-amino-7-[(2-carboxyethyl)thio]-1,4-dihydroquinoline-3-carboxylate. The latter synthon is obtained by reduction of the 8-nitro-1,4-dihydroquinoline precursor 8 which, in turn, is made accessible via interaction of 3-mercaptopropionate with 7-chloro-1-cyclopropyl-6-fluoro-8-nitro-1,4-dihydroquinoline-3-carboxylate (II) in the presence of Et3N. A benzo-homolog of I, namely tetrahydroquino[7,8-b]benzothiazepine-3-carboxylate, is analogously prepared via the reaction of 2-mercaptobenzoate with II, followed by reduction of the resulting 7-[(2-carboxyphenyl)thio]-8-nitro product into the corresponding 8-amino derivative, and subsequent lactamization.
Molecules published new progress about 924-99-2. 924-99-2 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Amine,Aliphatic hydrocarbon chain,Ester, name is Ethyl 3-(dimethylamino)acrylate, and the molecular formula is C7H13NO2, Computed Properties of 924-99-2.
Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics