Synthesis and in vitro antisickling activity of some non-aromatic esters was written by Tshilanda, Dorothee D.;Ngbolua, Koto-te-Nyiwa;Tshibangu, Damien S. T.;Malumba, Augustin M.;Mpiana, Pius T.. And the article was included in American Chemical Science Journal in 2016.Category: esters-buliding-blocks The following contents are mentioned in the article:
Organic acids and their derivatives like Bu stearate have recently shown antisickling activity. Some none aromatic esters were synthesized and tested for their antisickling activity using Emmel test. On 21 esters tested only three showed no antisickling activity. Bu palmitate, Pr palmitate, Bu stearate, Pr stearate and Me nonadecanoate showed interesting antisickling activity with a normalization rate higher than 70%. This study involved multiple reactions and reactants, such as Methyl nonadecanoate (cas: 1731-94-8Category: esters-buliding-blocks).
Methyl nonadecanoate (cas: 1731-94-8) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Category: esters-buliding-blocks
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics