C60 Fullerene with Tetraethylene Glycols as a Well-defined Soluble Building Block and Saccharide-conjugation Producing PDT Photosensitizer was written by Narumi, Atsushi;Nakazawa, Tatsufumi;Shinohara, Kosuke;Kato, Hiroki;Iwaki, Yoshinori;Okimoto, Haruya;Kikuchi, Moriya;Kawaguchi, Seigou;Hino, Shodai;Ikeda, Atsushi;Shaykoon, Montaser Shaykoon Ahmed;Shen, Xiande;Duan, Qian;Kakuchi, Toyoji;Yasuhara, Kazuma;Nomoto, Akihiro;Mikata, Yuji;Yano, Shigenobu. And the article was included in Chemistry Letters in 2019.Application of 604-69-3 The following contents are mentioned in the article:
Tetraethylene glycol (TEG)-conjugated (C60-Ih)[5,6]fullerene (TEG-C60) was synthesized as a soluble mol. building block generating C60-based conjugates with advanced properties. The improved solubility allowed the glycosylation reaction with TEG-C60 using a Lewis acid in chloroform at low temperature The resultant glycoconjugated TEG-C60 was characterized in terms of water solubility, ability to generate reactive oxygen species (ROS), and photodynamic activity. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Application of 604-69-3).
(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Application of 604-69-3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics