Enantioselective, Catalytic One-Pot Synthesis of γ-Butyrolactone-Based Fragrances was written by Kumru, Ceyda;Classen, Thomas;Pietruszka, Joerg. And the article was included in ChemCatChem in 2018.Recommanded Product: 106-73-0 The following contents are mentioned in the article:
Herein the preparative (1 g scale), stereoselective syntheses of various alkyl-substituted γ-butyrolactone fragrances is described. The α,β-unsaturated γ-keto esters as starting materials were synthesized by a Horner-Wadsworth-Emmons reaction and are further reduced by an ene reductase and alc. dehydrogenase in a one-pot enzyme cascade to nine desired γ-butyrolactones, among them whisky and cognac lactone. The products were obtained in moderate to good yields and very good diastereoselectivities. Furthermore, the position of a nBu-substituent was permutated to study the effect on the enzyme cascade. This study involved multiple reactions and reactants, such as Methyl heptanoate (cas: 106-73-0Recommanded Product: 106-73-0).
Methyl heptanoate (cas: 106-73-0) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Recommanded Product: 106-73-0
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics