Ligand-Enabled, Iridium-Catalyzed ortho-Borylation of Fluoroarenes was written by Kuleshova, Olena;Asako, Sobi;Ilies, Laurean. And the article was included in ACS Catalysis in 2021.Synthetic Route of C14H18BFO4 The following contents are mentioned in the article:
A terpyridine derivative and an iridium complex catalyze the C-H borylation of a stoichiometric amount of a fluoroarene with high ortho-selectivity and tolerance of functional groups such as bromide, chloride, ester, ketone, amine, and in situ-borylated hydroxyl. Complex drug mols. such as haloperidol can be selectively borylated ortho to the F atom. The terpyridine ligand undergoes rollover cyclometalation to produce an N,N,C-coordinated iridium complex, which may either selectively borylate the fluoroarene by itself or undergo reductive elimination to produce a borylated ligand. This study involved multiple reactions and reactants, such as Methyl 2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (cas: 1638847-77-4Synthetic Route of C14H18BFO4).
Methyl 2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (cas: 1638847-77-4) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Synthetic Route of C14H18BFO4
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics