Lewis acids as highly efficient catalysts for the decarboxylative esterification of carboxylic acids with dialkyl dicarbonates was written by Goossen, L.;Doehring, A.. And the article was included in Advanced Synthesis & Catalysis in 2003.Formula: C9H16O4 The following contents are mentioned in the article:
Mild Lewis acids such as Mg(ClO4)2 show a new level of catalytic activity for the decarboxylative esterification of carboxylic acids with com. available dialkyl dicarbonates. In the presence of as little as one mol % Mg(ClO4)2 catalyst, carboxylic acids can thus easily and near quant. be protected at room temperature, e.g., as Me, benzyl, or t-Bu esters. Only volatile byproducts are released so that the purification of the products is particularly easy. Many sensitive functionalities are tolerated, including even phenol esters, or free hydroxy and BOC groups. This study involved multiple reactions and reactants, such as Ethyl methyl adipate (cas: 18891-13-9Formula: C9H16O4).
Ethyl methyl adipate (cas: 18891-13-9) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Formula: C9H16O4
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics