Catalyst-Free and Scalable Process for Synthesis of Novel MAP4K4 Inhibitor DMX-5804 and Its Glyco-Conjugates was written by Eeda, Venkateswararao;Awasthi, Vibhudutta. And the article was included in Organic Process Research & Development in 2021.Computed Properties of C16H22O11 The following contents are mentioned in the article:
Here, the process development of scalable and practical synthesis of DMX-5804 I was reported. Process optimization resulted in the following, removal of transition metals from the process and reduced duration of reactions, a streamlined process with significantly improved yields using low-cost raw materials, importantly, microwave-assisted reactions were removed, column purification avoided throughout the process, and crystallized products showed over 95% purity in each step. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Computed Properties of C16H22O11).
(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Computed Properties of C16H22O11
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics