Reactions of (Trialkylsilyl)vinylketenes with Lithium Ynolates: A New Benzannulation Strategy was written by Austin, Wesley F.;Zhang, Yongjun;Danheiser, Rick L.. And the article was included in Organic Letters in 2005.Safety of Ethyl 3-ethoxypropanoate The following contents are mentioned in the article:
(Trialkylsilyl)vinylketenes I [R1 = Me, R2 = Me, Et, cyclohexyl; R1R2 = (CH2)4] react with lithium ynolates, generated from ethynyl silyl ethers R3CCOSiR42R5 (R3 = Me2CH, n-Bu, 1-cyclohexenyl, etc.; R4 = R5 = Me2CH; R4 = Me, R5 = Me3C) to produce highly substituted phenols II in a new benzannulation strategy that proceeds via the 6π electrocyclization of an intermediate 3-(oxido)dienylketene. This study involved multiple reactions and reactants, such as Ethyl 3-ethoxypropanoate (cas: 763-69-9Safety of Ethyl 3-ethoxypropanoate).
Ethyl 3-ethoxypropanoate (cas: 763-69-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Safety of Ethyl 3-ethoxypropanoate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics