Tsukamoto, Issei’s team published research in Bioorganic & Medicinal Chemistry in 17 | CAS: 220141-23-1

Bioorganic & Medicinal Chemistry published new progress about 220141-23-1. 220141-23-1 belongs to esters-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Benzene,Ester, name is Methyl 4-fluoro-2-(trifluoromethyl)benzoate, and the molecular formula is C7H13BrSi, Name: Methyl 4-fluoro-2-(trifluoromethyl)benzoate.

Tsukamoto, Issei published the artcileOptimization of (4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine-5-ylidene)acetamide derivatives as arginine vasopressin V2 receptor agonists and discussion of their binding modes, Name: Methyl 4-fluoro-2-(trifluoromethyl)benzoate, the publication is Bioorganic & Medicinal Chemistry (2009), 17(24), 8161-8167, database is CAplus and MEDLINE.

A series of (4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine-5-ylidene)acetamide derivatives were optimized to achieve potent agonistic activity, both in vitro and in vivo, for the arginine vasopressin V2 receptor, resulting in the eventual discovery of compound 1g. Mol. modeling of compound 1g with V2 receptor was also examined to evaluate the binding mode of this series of compounds

Bioorganic & Medicinal Chemistry published new progress about 220141-23-1. 220141-23-1 belongs to esters-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Benzene,Ester, name is Methyl 4-fluoro-2-(trifluoromethyl)benzoate, and the molecular formula is C7H13BrSi, Name: Methyl 4-fluoro-2-(trifluoromethyl)benzoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics