Consecutive Michael-Claisen process for cyclohexane-1,3-dione derivative (CDD) synthesis from unsubstituted and substituted acetone was written by Sharma, Dharminder;Bandna;Shil, Arun K.;Singh, Bikram;Das, Pralay. And the article was included in Synlett in 2012.COA of Formula: C7H14O3 The following contents are mentioned in the article:
A long-existing problem of cyclohexane-1,3-dione synthesis from unreactive acetone through consecutive Michael-Claisen process was solved. The practical applicability of this process was tested for 3-(2,4-dioxocyclohexyl)propanoate for â?0-g scale. Furthermore, the scope of different acetone derivatives was investigated and resulted with a similar consecutive Michael-Claisen process for CDD synthesis. The reaction exhibited remarkable regioselectivity in Michael addition followed by Claisen cyclization. In this process high substrate selectivity was observed for CDD synthesis following consecutive double-Michael-Claisen and Michael-Claisen cyclization. This study involved multiple reactions and reactants, such as Ethyl 3-ethoxypropanoate (cas: 763-69-9COA of Formula: C7H14O3).
Ethyl 3-ethoxypropanoate (cas: 763-69-9) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.COA of Formula: C7H14O3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics