Synthetic studies directed toward cembranolides. Synthesis of the basic nucleus of crassin acetate was written by Dauben, William G.;Saugier, R. Kent;Fleischhauer, Ilona. And the article was included in Journal of Organic Chemistry in 1985.SDS of cas: 37905-02-5 The following contents are mentioned in the article:
A stereospecific synthesis of the basic crassin acetate nucleus, erythro-1-(hydroxymethyl)-14-hydroxy-4,8,12-trimethylcyclotetradeca-(E,E,E)-3,7,11-triene, was achieved. Stereospecific syntheses of the 2 precursors to this ring system, (E,E)-3,7-dimethyl-9-(phenylthio)nona-3,7-dienal and (E)-2,8-bis(trimethylsiloxy)-2,7-dimethyloct-6-en-3-one were developed. Aldol condensation of these 2 compounds gave erythro-9-hydroxy-10-[1-oxo-2-methyl-2-(trimethylsiloxy)propyl]-1-(phenylthio)-14-(trimethylsiloxy)-3,7,13-trimethyltetradeca-(E,E,E)-2,6,12-triene, which was cyclized to the titled 14-membered ring system in several steps. This study involved multiple reactions and reactants, such as (2E,6E)-3,7-Dimethyl-8-oxoocta-2,6-dien-1-yl acetate (cas: 37905-02-5SDS of cas: 37905-02-5).
(2E,6E)-3,7-Dimethyl-8-oxoocta-2,6-dien-1-yl acetate (cas: 37905-02-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.SDS of cas: 37905-02-5
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics