Chotana, Ghayoor A. published the artcileIridium-catalyzed borylation of thiophenes: versatile, synthetic elaboration founded on selective C-H functionalization, Recommanded Product: Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-3-carboxylate, the publication is Tetrahedron (2008), 64(26), 6103-6114, database is CAplus and MEDLINE.
Iridium-catalyzed borylation has been applied to various substituted thiophenes to synthesize poly-functionalized thiophenes in good to excellent yields. Apart from common functionalities compatible with iridium-catalyzed borylations, addnl. functional group tolerance to acyl (COMe) and trimethylsilyl (TMS) groups was also observed High regioselectivities were observed in borylation of 3- and 2,5-di-substituted thiophenes. Electrophilic aromatic C-H/C-Si bromination on thiophene boronate esters is shown to take place without breaking the C-B bond, and one-pot C-H borylation/Suzuki-Miyaura cross-coupling has been accomplished on 2- and 3-borylated thiophenes.
Tetrahedron published new progress about 1040281-86-4. 1040281-86-4 belongs to esters-buliding-blocks, auxiliary class Thiophene,Boronic acid and ester,Ester,Boronate Esters,Boronic Acids,Boronic acid and ester,Boronate Esters,, name is Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-3-carboxylate, and the molecular formula is C12H17BO4S, Recommanded Product: Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-3-carboxylate.
Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics