Cobalt-Catalyzed Asymmetric Hydrogenation of 1,1-Diarylethenes was written by Chen, Jianhui;Chen, Chenhui;Ji, Chonglei;Lu, Zhan. And the article was included in Organic Letters in 2016.Computed Properties of C12H13FO3 The following contents are mentioned in the article:
Highly enantioselective cobalt-catalyzed hydrogenation of 1,1-diarylethenes was developed by using bench-stable chiral oxazoline iminopyridine-cobalt complexes as precatalysts. Thus, (vinylphenyl)pyrrole I gave (phenylethyl)pyrrole II in 97% yield and 92% ee. A unique o-chloride effect was observed to achieve high enantioselectivity. Easy removal as well as further transformations of the chloro group make this protocol a potentially useful alternative to synthesize various chiral 1,1-diarylethanes. This process can be successfully performed under 1 atm of hydrogen at room temperature on gram scale. This study involved multiple reactions and reactants, such as Methyl 5-(4-fluorophenyl)-5-oxopentanoate (cas: 149437-67-2Computed Properties of C12H13FO3).
Methyl 5-(4-fluorophenyl)-5-oxopentanoate (cas: 149437-67-2) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Computed Properties of C12H13FO3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics