Wang, Junlei published the artcileVisible-light-mediated defluorinative cross-coupling of gem-difluoroalkenes with thiols, Computed Properties of 19788-49-9, the publication is Chemical Communications (Cambridge, United Kingdom) (2019), 55(74), 11103-11106, database is CAplus and MEDLINE.
A visible-light-mediated monofluoroalkenylation through defluorinative cross-coupling of gem-difluoroalkenes RR1C=CF2 [R = biphenyl-4-yl, 1-benzofuran-2-yl, 4-(trifluoromethyl)phenyl, etc.; R1 = H, Ph, 3-(trifluoromethyl)phenyl, 4-methoxyphenyl, etc.; RR1 = 9H-fluoren-9-yl, [2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy- 2,3-dihydro-1H-inden-1-yl]] with aryl, benzyl, and alkyl thiols R2SH (R2 = cyclohexyl, 4-methoxyphenyl, 2-bromophenyl, etc.) has been reported. This novel strategy provides facile and efficient access to tri/tetra-substituted monofluoroalkenes RR1C=C(F)SR2 under mild reaction conditions with good functional group tolerance. Late-stage modification of natural products such as dehydrocholic acid and diosgenin indicated the synthetic potential of this S-H monofluoroalkenylation process.
Chemical Communications (Cambridge, United Kingdom) published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C14H22O2, Computed Properties of 19788-49-9.
Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics