Shinagawa, Yuko’s team published research in Bioorganic & Medicinal Chemistry Letters in 20 | CAS: 115314-17-5

Bioorganic & Medicinal Chemistry Letters published new progress about 115314-17-5. 115314-17-5 belongs to esters-buliding-blocks, auxiliary class Epoxides,Chiral,Nitro Compound,Sulfonate,Benzene, name is (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate, and the molecular formula is C19H14O2, Synthetic Route of 115314-17-5.

Shinagawa, Yuko published the artcileNew aminopropanediol derivatives as orally available and short-acting calcium-sensing receptor antagonists, Synthetic Route of 115314-17-5, the publication is Bioorganic & Medicinal Chemistry Letters (2010), 20(12), 3809-3813, database is CAplus and MEDLINE.

Synthesis and structure-activity relationship studies on new aminopropanediol derivatives I (R1 = Ph, R2 = H, Me, H2C:CHCH2, t-Bu, cyclopentyl, Ph, etc.; R1 = 2-pyridyl, 1-naphthyl, 2-naphthyl, R2 = Me; etc.) as calcium-sensing receptor antagonists are described. Modification of the phenolic moiety of a calcilytic compound NPS 2143 led to the identification of an orally available compound (R,R)-I (R1 = 2-MeC6H4; R2 = cyclopropyl) which demonstrated a rapid and transient stimulation of PTH release in rats.

Bioorganic & Medicinal Chemistry Letters published new progress about 115314-17-5. 115314-17-5 belongs to esters-buliding-blocks, auxiliary class Epoxides,Chiral,Nitro Compound,Sulfonate,Benzene, name is (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate, and the molecular formula is C19H14O2, Synthetic Route of 115314-17-5.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics