Analgesic and antiinflammatory properties of some new salicylic acid derivatives, including QSAR was written by Langner, A.;Hagen, V.;Labes, D.;Krause, E.. And the article was included in Agents and Actions Supplements in 1982.Quality Control of 4-Acetamidophenyl 2-acetoxybenzoate The following contents are mentioned in the article:
Results from analgesic (hot-plate and radiant-heat methods) and antiinflammatory (carrageenin rat paw edema) activity screening in 21 salicylates showed that only 4 compounds [acetylsalicylic acid piperidide, pyrrolidide (I), p-hydroxyanilide [19065-81-7], and 2-pyrimidylamide [71924-69-1] derivatives] had analgesic activity comparable to that of acetylsalicylic acid and only 4 (I and the acetylsalicylic acid p-nitranilide [25671-41-4], α-pyridylamide, and 2-nitro-4-methoxyanilide [36930-83-3] derivatives) had antiinflammatory activity comparable to that of salicylamide. The remaining substances were either weakly active or inactive. Hansch anal. was performed on a selected number of the substances and the results are discussed in relation to structural requirements for activity. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Quality Control of 4-Acetamidophenyl 2-acetoxybenzoate).
4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Quality Control of 4-Acetamidophenyl 2-acetoxybenzoate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics