Gemborys, Mark W. published the artcileSynthesis of N-hydroxyacetaminophen, a postulated toxic metabolite of acetaminophen, and its phenolic sulfate conjugate, Quality Control of 6217-68-1, the publication is Journal of Medicinal Chemistry (1978), 21(7), 649-52, database is CAplus and MEDLINE.
The synthesis of N-hydroxyacetaminophen (I) [63975-21-3], a postulated toxic metabolite of acetaminophen, and its phenolic sulfate conjugate II [66682-85-7] is described. K p-nitrophenyl sulfate [6217-68-1] was reduced, acetylated, and treated with sulfatase to give I. I was moderately unstable at physiol. pH and temperature, but II was stable.
Journal of Medicinal Chemistry published new progress about 6217-68-1. 6217-68-1 belongs to esters-buliding-blocks, auxiliary class Salt,Nitro Compound,Sulfonate,Benzene, name is Potassium 4-nitrophenyl sulfate, and the molecular formula is C6H4KNO6S, Quality Control of 6217-68-1.
Referemce:
https://en.wikipedia.org/wiki/Ester,
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