Month: November 2022

Zhang, Ruijie K. published the artcileEnzymatic assembly of carbon-carbon bonds via iron-catalysed sp³ C-H functionalization, Recommanded Product: 3-Acetyldihydrofuran-2(3H)-one, the publication is Nature (London, United Kingdom) (2019), 565(7737), 67-72, database is CAplus and MEDLINE.

Although abundant in organic mols., carbon-hydrogen (C-H) bonds are typically considered unreactive and unavailable for chem. manipulation. Recent advances in C-H functionalization technol. have begun to transform this logic, while emphasizing the importance of and challenges associated with selective alkylation at a sp³ carbon. Here we describe iron-based catalysts for the enantio-, regio- and chemoselective intermol. alkylation of sp³ C-H bonds through carbene C-H insertion. The catalysts, derived from a cytochrome P 450 enzyme in which the native cysteine axial ligand has been substituted for serine (cytochrome P411), are fully genetically encoded and produced in bacteria, where they can be tuned by directed evolution for activity and selectivity. That these proteins activate iron, the most abundant transition metal, to perform this chem. provides a desirable alternative to noble-metal catalysts, which have dominated the field of C-H functionalization. The laboratory-evolved enzymes functionalize diverse substrates containing benzylic, allylic or α-amino C-H bonds with high turnover and excellent selectivity. Furthermore, they have enabled the development of concise routes to several natural products. The use of the native iron-haem cofactor of these enzymes to mediate sp³ C-H alkylation suggests that diverse haem proteins could serve as potential catalysts for this abiol. transformation, and will facilitate the development of new enzymic C-H functionalization reactions for applications in chem. and synthetic biol.

Nature (London, United Kingdom) published new progress about 517-23-7. 517-23-7 belongs to esters-buliding-blocks, auxiliary class Tetrahydrofuran,Ketone,Ester, name is 3-Acetyldihydrofuran-2(3H)-one, and the molecular formula is C9H8BNO2, Recommanded Product: 3-Acetyldihydrofuran-2(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Han, Junyong published the artcileExperimental study on the effect of dimethyl itaconate on insulitis in non-obese diabetic mice, Formula: C7H10O4, the publication is Fujian Yiyao Zazhi (2021), 43(6), 122-125, database is CAplus.

Objective To investigate the effect of di-Me itaconate on insulitis in NOD mice. Methods The phenotypic changes of RAW 264.7 macrophages induced by di-Me itaconate were detected by flow cytometry, and the effect of di-Me itaconate on the secretion of RAW 264.7 cytokines (IL-6, IL-12 and TNF-α) were observed by ELISA. At the same time, di-Me itaconate was injected i.p. into NOD mice to further explore its effect on islet inflammation. Results Di-Me itaconate reduced the M1/M2 ratio of macrophages and converted macrophages to M2 type, and also reduced the secretion of IL-6, IL-12 and TNF-α. The islet score of 50 mg/kg di-Me itaconate reached 1.115±0.7821. Conclusion Di-Me itaconate can alleviate insulitis in NOD mice by phenotypic transformation of M1/M2 macrophages.

Fujian Yiyao Zazhi published new progress about 617-52-7. 617-52-7 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Aliphatic hydrocarbon chain,Ester, name is Dimethyl itaconate, and the molecular formula is C7H10O4, Formula: C7H10O4.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Chen, Jing published the artcilePhase inversion of pickering emulsion stabilized by adipate-functionalized SiO₂ particles, Recommanded Product: Dimethyl adipate, the publication is Gaodeng Xuexiao Huaxue Xuebao (2020), 41(1), 140-144, database is CAplus.

Phase inversion of emulsion of dialkyl adipate-water mixture stabilized by adipate-functionalized SiO₂ particles was described. Ability of different adipate to functionalize SiO₂ particles for Pickering emulsion was investigated systematically. Chain length of alkyl in adipates was found to be crucial to the property of formed emulsion. Adipate with long alkyl chain was apt to form oil-in-water emulsion, while adipate with short alkyl chain was apt to form water-in-oil emulsion. The reason of this difference was explored by analyzing the phase inversion. Adipate with short alkyl chain has strong hydrogen bonding ability with Si-OH on SiO₂ particles. Fourier transform IR (FTIR) spectra verified directly the difference of adipate archored on SiO₂ particles. Properties of emulsion prepared under pH=9 reconfirmed the proposed mechanism.

Gaodeng Xuexiao Huaxue Xuebao published new progress about 627-93-0. 627-93-0 belongs to esters-buliding-blocks, auxiliary class Ploymers, name is Dimethyl adipate, and the molecular formula is C8H14O4, Recommanded Product: Dimethyl adipate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Ananth, Ramagopal published the artcileOptical purification of chiral glycidyl arenesulfonates, Application In Synthesis of 115314-17-5, the publication is Tetrahedron: Asymmetry (1995), 6(2), 317-20, database is CAplus.

The m.p. point phase diagrams of glycidyl tosylate (1), glycidyl 3-nitrobenzenesulfonate (2), and trans-3-methylglycidyl tosylate (3) have been investigated. Compounds 1 and 2 exhibit a more significant solid solution behavior in the terminal zones of the phase diagram than 3, and are therefore more difficult to enrich enantiomerically by recrystallizations The crystallization of 2 in ethanol is further complicated by polymorphism which can be followed by differential scanning calorimetry. The effects of these properties on the optical purification of 1–3 are discussed.

Tetrahedron: Asymmetry published new progress about 115314-17-5. 115314-17-5 belongs to esters-buliding-blocks, auxiliary class Epoxides,Chiral,Nitro Compound,Sulfonate,Benzene, name is (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate, and the molecular formula is C9H9NO6S, Application In Synthesis of 115314-17-5.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Sun, Ke published the artcileHigh-performance sunlight induced polymerization using novel push-pull dyes with high light absorption properties, Recommanded Product: Ethyl 4-dimethylaminobenzoate, the publication is European Polymer Journal (2021), 110410, database is CAplus.

In this article, a series of three-component photoinitiating systems (PISs) based on push-pull dyes are proposed. The systems are composed of the newly synthesized push-pull dyes and different co-initiators, namely an iodonium salt and a tertiary amine (Et dimethylaminobenzoate EDB). Photoinitiation abilities and photochem. properties of the different investigated photoinitiating systems were studied in detail. Notably, the mechanisms related to the polymerization efficiencies were determined using different techniques such as UV-visible absorption and fluorescence spectroscopy. Moreover, the photoinitiation abilities of the three-component systems for the sunlight-induced polymerization processes were also examined, indicating that sunlight can act as an effective light source for photopolymerization Finally, 3D patterns with a spatial resolution were successfully produced by the direct laser writing (DLW) approach, even with photosensitive resins containing silica fillers.

European Polymer Journal published new progress about 10287-53-3. 10287-53-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Ester, name is Ethyl 4-dimethylaminobenzoate, and the molecular formula is C10H15NS, Recommanded Product: Ethyl 4-dimethylaminobenzoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Xu, Kangming published the artcileTransparent, self-recoverable, highly tough, puncture and tear resistant polyurethane supramolecular elastomer with fast self-healing capacity via “hard-soft” hard domain design, Recommanded Product: 3-Acetyldihydrofuran-2(3H)-one, the publication is RSC Advances (2022), 12(5), 2712-2720, database is CAplus and MEDLINE.

The integration of superior mech. properties and fast healing efficiency for self-healing polyurethane supramol. elastomers is challenging due to the confliction between high chain mobility for healing and high chain rigidity for mech. properties. Herein, a strategy to design a “hard-soft” hard domain by the cooperation of quadruple hydrogen bonds (HBs) in the mainchain as restriction units and single HBs in the side chain as diffusion units is reported. The resulting transparent supramol. elastomer exhibited fast self-recoverability, good puncture resistance and superior mech. properties with a tensile strength of 20.5 MPa, an extensibility of 2043.7%, a toughness of 146.1 MJ m^-3 and a tear resistance of 13.8 kJ m^-2. Moreover, the fast self-healing capacity (healing efficiency > 82% within 3 h under moderate condition) was realized due to the soft effects of weak HBs in the side chain on the strong HBs in the mainchain. Taking advantage of the merits of the supramol. elastomer, a flexible sensor was simply fabricated, which showed good self-repairable and stable sensing properties. Thus, the elastomer has great potential in the field of flexible electronics and wearable devices.

RSC Advances published new progress about 517-23-7. 517-23-7 belongs to esters-buliding-blocks, auxiliary class Tetrahydrofuran,Ketone,Ester, name is 3-Acetyldihydrofuran-2(3H)-one, and the molecular formula is C7H3Cl2F3O2S, Recommanded Product: 3-Acetyldihydrofuran-2(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Chen, Yu-Hao published the artcileSynthesis and characterization of low-temperature polyamide 6 (PA6) copolyamides used as hot melt adhesives and derived from the comonomer of novel aliphatic diamine bis(2-aminoethyl) adipamide and adipic acid, Synthetic Route of 627-93-0, the publication is International Journal of Adhesion and Adhesives (2020), 102619, database is CAplus.

A novel aliphatic PA6 copolyamide (PA6(BAEA/AA))-based hot melt adhesive was synthesized from ε-caprolactam with the organic salt of bis(2-aminoethyl) adipamide (BAEA) and adipic acid (AA), with BAEA/AA content ranges from 5 to 15 mol%. The chem. structures of BAEA diamine, BAEA/AA organic salt, PA6(BAEA/AA) copolyamides, and neat PA6 were obtained using FT-IR and ¹H NMR. Determined by the comonomer compositions, the relative viscosity and mol. weight (Mw) of the PA6(BAEA/AA) were from 2.29 to 2.74 and from 14,530 to 19,500 g mol^-1, resp. Adding the BAEA/AA structure strongly affected the crystallization behavior and thermal properties of the copolyamides. DSC results revealed that the melting temperature (T_m) of the copolyamides declined as the mole% of BAEA/AA increased in the range 5-15 mol%, and a TGA test revealed that the thermal decomposition of the copolyamides was similar to that of neat PA6. The Tm, glass transition temperature (T_g), and thermal stability (Td5%) with a BAEA/AA salt content of 10 mol% had the lowest values of 162.2, 40.3, 354.6°C, resp., while the fusion enthalpy (ΔHm) was lowest at 15 mol% (21.2 J g^-1). Most remarkably, PA6(BAEA/AA) exhibits much better mech. properties such as tensile strength (33.6-52.6 MPa) and elongation at breakage (114.7-584.5%), than the PA6 homopolymer. The peel strength of PA6 reached a maximum value of 53.4 N cm^-1 at 10 mol% of BAEA/AA salt, and this value is better than those of com. hot melt adhesives.

International Journal of Adhesion and Adhesives published new progress about 627-93-0. 627-93-0 belongs to esters-buliding-blocks, auxiliary class Ploymers, name is Dimethyl adipate, and the molecular formula is C8H14O4, Synthetic Route of 627-93-0.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Ioriatti, C. published the artcileStudy of the principal factors influencing the emission of synthetic sex attractants from rubber and plastic diffusers, Recommanded Product: (Z)-Dodec-9-en-1-yl acetate, the publication is Entomologia Experimentalis et Applicata (1987), 44(2), 123-30, database is CAplus.

To determine the effect of various factors influencing the emission rate of pheromones from slow release dispensers, laboratory tests were undertaken with two types of rubber (Michelin) and one type of plastic trilaminate (Hercon) dispenser. The effects of chain length, and the presence of double bonds were tested with three pheromonal compounds, (Z)-9-dodecenyl acetate, (Z)-9-tetradecenyl acetate, and dodecenyl acetate impregnated on both types of rubber dispenser. The influences of temperature, wind velocity, humidity and percent loading were also tested. Data obtained indicated that chain length has a greater effect than the presence of a double bond. Among the climatic factors tested, wind speed has a greater effect than temperature while humidity has a minimal effect.

Entomologia Experimentalis et Applicata published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C14H26O2, Recommanded Product: (Z)-Dodec-9-en-1-yl acetate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Sridhar, Kandi published the artcileGrape skin extracts as a sustainable source of antioxidants in an oil-in-water emulsion: an alternate natural approach to synthetic antioxidants using principal component analysis, Formula: C10H12O5, the publication is International Journal of Food Science and Technology (2021), 56(4), 1937-1945, database is CAplus.

Grape (Kyoho) skin, used to retard lipid oxidation in edible oil foods, was investigated to reduce lipid oxidation in an oil-in-water (O/W) emulsion during 20 day of storage. The antioxidant efficacy of Kyoho skin extracts in O/W emulsions was determined by the measurement of secondary oxidation products. Moreover, principal component anal. (PCA) was conducted to determine similarities between emulsions treated with or without Kyoho skin extracts and standards The data revealed that Kyoho skin extracts exhibited >93% inhibition and reported a similar p-anisidine (4.30-20.71) and TBARS (6.08-11.15 mg MDA L^-1) values over the standards during 20 day of storage. PCA (PCs 1 (51.83%) and 2 (18.85%)) demonstrated a similarity in the contribution of Kyoho skin extracts over the synthetic antioxidants in O/W emulsion. Overall, these findings highlighted the possibility of using Kyoho skin extracts as natural antioxidants to decrease oxidative rancidity in foods.

International Journal of Food Science and Technology published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C2H2N4O2, Formula: C10H12O5.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Tang, Jie published the artcilePreparation of photosensitive SiO₂SiC ceramic slurry with high solid content for stereolithography, Related Products of esters-buliding-blocks, the publication is Ceramics International, database is CAplus.

Stereolithog. is a popular three-dimensional (3D) printing technol., which is widely used for manufacturing ceramic components owing to its high efficiency and precision. However, it is a big challenge to prepare SiC ceramic slurry with high solid content for stereolithog. due to the strong light absorption and high refractive index of dark SiC powders φ. Here, we propose a novel strategy to develop photosensitive SiO₂/SiC ceramic slurry with high solid content of 50-65 vol% by adding spherical silica with low light absorbance and applying a stacking flow model to improve the solid content of the slurry. The as-prepared slurry exhibits excellent stereolithog. properties with a dynamic viscosity lower than 20 Pa s and curing thickness more than 120 μm. Therefore, it can be successfully applied for stereolithog.-based additive manufacturing of SiC green ν bodies with large size (100 mm), sub-millimeter accuracy (0.2 mm), and complex structure. The stacking flow model also shows immense potential for the stereolithog. of other dark-color ceramics with high solid content.

Ceramics International published new progress about 15625-89-5. 15625-89-5 belongs to esters-buliding-blocks, auxiliary class Polymerization Reagents,Crosslinkers, name is Trimethylolpropane triacrylate, and the molecular formula is C14H12N2S, Related Products of esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics