Month: November 2022

Struble, D. L. published the artcileSex pheromone components of an Alberta population of European corn borer, Ostrinia nubilalis (HBN.) (Lepidoptera: Pyralidae), Formula: C14H26O2, the publication is Canadian Entomologist (1987), 119(3), 291-9, database is CAplus.

The sex pheromone components of European corn borer, O. nubilalis, from southern Alberta were identified in washes and extracts of abdomen tips from calling female moths. This is a Z strain population as (Z)-11- [20711-10-8] and (E)-11-tetradecenyl acetate  [33189-72-9] were isolated in a ratio 100:1.4, and a corresponding synthetic blend in a ratio of 100:3 attracted males in the field. Dodecyl alc.  [112-53-8], tetradecyl alc.  [112-72-1] and acetate [638-59-5], and (Z)-11-tetradecenol  [34010-15-6] were also identified, but none of these components nor other pheromone-like mono-unsaturated C₁₀ to C₁₆ acetates had any effect on increasing the trap catches of male moths under field conditions. However, the addition of (Z)-9-dodecenyl acetate  [16974-11-1] or (Z)-9-tetradecenyl acetate  [16725-53-4] to the synthetic pheromone blend significantly reduced the capture of male moths, even though these compounds were not detectable in the female extracts Pheromone blends used for monitoring the Z strain of the European corn borer must be essentially free, ca<0.1%, of these acetates. A com. available, sticky-surface, delta-type trap was the most satisfactory of several tested for capturing moths under prairie conditions.

Canadian Entomologist published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C15H20O6, Formula: C14H26O2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Takeoka, Gary R. published the artcileCyclic esters: compounds possessing remarkably low odor thresholds, Application of Ethyltert-butylacetate, the publication is Lebensmittel-Wissenschaft und -Technologie (1991), 24(6), 569-70, database is CAplus.

A series of cyclic esters (Et cyclopropanecarboxylate to Et cyclooctanecarboxylate) were synthesized and their odor thresholds were determined using sensory panel methods. Ring size had a dramatic effect on the odor potency of the esters. The odor thresholds reached a min. (0.001 ppb) with the cyclopentane and cyclohexane ring substituents. While increasing the ring size had only a slight effect on the odor threshold, smaller ring substituents had much higher odor thresholds. The effect of double bond position in the cyclohexane ring on the odor threshold was also examined

Lebensmittel-Wissenschaft und -Technologie published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C38H74Cl2N2O4, Application of Ethyltert-butylacetate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Silk, P. J. published the artcileIdentification of sex pheromone component of spruce budmoth Zeiraphera canadensis, Related Products of esters-buliding-blocks, the publication is Journal of Chemical Ecology (1989), 15(10), 2435-44, database is CAplus and MEDLINE.

The analyses of virgin female sex pheromone gland extracts by gas chromatog. (GC), GC-electroantennog. detection and GC-mass spectrometry followed by field-trapping experiments, have identified (E)-9-tetradecenyl acetate (E9-14:Ac) as the primary sex pheromone component of the spruce budmoth, Z. canadensis. Dosages of 1.0-100.0 μg of E9-14:Ac impregnated in rubber septa provide effective trap baits.

Journal of Chemical Ecology published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C10H12F6N4O6PdS2, Related Products of esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Edwards, Jonathan D published the artcileEffect of the Butyrate Prodrug Pivaloyloxymethyl Butyrate (AN9) on a Mouse Model for Spinal Muscular Atrophy., Application of (Pivaloyloxy)methyl butyrate, the publication is Journal of neuromuscular diseases (2016), 3(4), 511-515, database is MEDLINE.

Spinal muscular atrophy (SMA) is an early-onset motor neuron disease that leads to loss of muscle function. Butyrate (BA)-based compounds markedly improve the survival and motor phenotype of SMA mice. In this study, we examine the protective effects of the BA prodrug pivaloyloxymethyl butyrate (AN9) on the survival of SMNΔ7 SMA mice. Oral administration of AN9 beginning at PND04 almost doubled the average lifespan of SMNΔ7 SMA mice. AN9 treatment also increased the growth rate of SMNΔ7 SMA mice when compared to vehicle-treated SMNΔ7 SMA mice. In conclusion, BA prodrugs like AN9 have ameliorative effects on SMNΔ7 SMA mice.

Journal of neuromuscular diseases published new progress about 122110-53-6. 122110-53-6 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ester,Inhibitor, name is (Pivaloyloxy)methyl butyrate, and the molecular formula is C10H18O4, Application of (Pivaloyloxy)methyl butyrate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Hermann, Aurelien published the artcileComparative study of the impact of additives against oxygen inhibition on pendulum hardness and abrasion resistance for UV-curable wood finishes, Name: Ethyl 4-dimethylaminobenzoate, the publication is Progress in Organic Coatings (2021), 106266, database is CAplus.

The multiple advantages of UV-curable coatings, such as high curing speeds and crosslinking densities, low VOC and energy consumption led to a widespread interest for a wide range of applications. Free-radical photopolymerization constitutes one of the most used methods of polymerization However, oxygen present in the atm. is able to inhibit radical formation and propagation, which is considered a major drawback. Among all the strategies developed for reducing the oxygen inhibition, the addition of reactive additives is often preferred. This method does not require major changes in the production lines of the industries or in the formulations compositions The efficiency of reactive additives against oxygen inhibition has been investigated in multiple studies, but in different exptl. conditions. The addition of the reactive additives can also influence coatings hardness and abrasion resistance, which are considered important mech. properties. The aim of this study is to evaluate additives overall performances. Eleven of the chosen additives were previously described in the literature. The four remaining are com. products never used for that application, such as a polyhedral oligomeric silsesquioxane bearing a thiol function, which later showed some of the best results. Reduction of oxygen inhibition was analyzed by photo differential scanning calorimetry (Photo-DSC) and Confocal Raman Micro-spectroscopy (CRM). Pendulum hardness and abrasion resistance measurements were used to determine the influence of the additives on the mech. properties of the coatings. The results obtained show that most of the additives tested had reducing effect on the pendulum hardness, but helped in improving the abrasion resistance.

Progress in Organic Coatings published new progress about 10287-53-3. 10287-53-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Ester, name is Ethyl 4-dimethylaminobenzoate, and the molecular formula is C11H15NO2, Name: Ethyl 4-dimethylaminobenzoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Fobi, Kwabena published the artcileDomino Nitro Reduction-Friedlander Heterocyclization for the Preparation of Quinolines, Formula: C6H10O3, the publication is Molecules (2022), 27(13), 4123, database is CAplus and MEDLINE.

The Friedlander synthesis offers efficient access to substituted quinolines from 2-aminobenzaldehydes and activated ketones in the presence of a base. The disadvantage of this procedure lies in the fact that relatively few 2-aminobenzaldehyde derivatives are readily available. To overcome this problem, authors report a modification of this process involving the in situ reduction of 2-nitrobenzaldehydes with Fe/AcOH in the presence of active methylene compounds (AMCs) to produce substituted quinolines in high yields. The conditions are mild enough to tolerate a wide range of functionality in both reacting partners and promote reactions not only with Ph and benzyl ketones, but also with β-keto-esters, β-keto-nitriles, β-keto-sulfones and β-diketones. The reaction of 2-nitroarom. ketones with unsym. AMCs is less reliable, giving a competitive formation of substituted quinolin-2(1H)-ones from the cyclization of the Z Knoevenagel intermediate which appears to be favored when certain large groups are adjacent to the AMC ketone carbonyl.

Molecules published new progress about 30414-53-0. 30414-53-0 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ketone,Ester, name is Methyl 3-oxovalerate, and the molecular formula is C6H10O3, Formula: C6H10O3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Gracia, Jordi published the artcileBiphenyl Pyridazinone Derivatives as Inhaled PDE4 Inhibitors: Structural Biology and Structure-Activity Relationships, Name: Methyl 4-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate, the publication is Journal of Medicinal Chemistry (2016), 59(23), 10479-10497, database is CAplus and MEDLINE.

Cyclic nucleotide cAMP is an ubiquitous second messenger involved in a plethora of cellular responses to biol. agents involving activation of adenylyl cyclase. Its intracellular levels are tightly controlled by a family of cyclic nucleotide degrading enzymes, the PDEs. In recent years, cyclic nucleotide phosphodiesterase type 4 (PDE4) has aroused scientific attention as a suitable target for anti-inflammatory therapy in respiratory diseases, particularly in the management of asthma and COPD. Here the authors describe efforts to discover novel, highly potent inhaled inhibitors of PDE4. Through structure based design, with the intervention of a wide variety of functional groups and physichochem. profiles to occupy the solvent-filled pocket of the PDE4 enzyme, the authors modified the structure of the authors’ oral PDE4 inhibitors to reach compounds up to picomolar enzymic potencies. In vitro potencies were demonstrated in a rat lung neutrophilia model by suspension microspray administration.

Journal of Medicinal Chemistry published new progress about 757982-31-3. 757982-31-3 belongs to esters-buliding-blocks, auxiliary class Boronic acid and ester,Boronic acid and ester, name is Methyl 4-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate, and the molecular formula is C14H18BFO4, Name: Methyl 4-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Mozuraitis, R. published the artcileNew sex attractants and inhibitors for 17 moth species from the families Gracillariidae, Tortricidae, Yponomeutidae, Oecophoridae, Pyralidae and Gelechiidae, HPLC of Formula: 16974-11-1, the publication is Journal of Applied Entomology (1998), 122(8), 441-452, database is CAplus.

Field screening tests of 21 saturated and monounsaturated straight chain C₁₂ and C₁₄ alcs. and their acetates as well as some binary mixtures in dosages of 1 and 0.2 mg/dispenser were carried out in Lithuanian in 1993 and 1994. New sex attractants were determined for males of five moth species of the family Gracillariidae (E10-12:OH for Phyllonorycter sorbi, E10-12Ac for Ph. cydoniella and Ph. oxyacanthae, Z10-12:OAc for Ph. junoniella, and a mixture of Z10-14:OAc with E9-14:OAc in a 1:10 for Ph. sylvella), for four species of the family Tortricidae (E10-14:OAc for Endothenia ericetana, Z10-14:OAc in a 10:1 mixture with E11-14:OAc for Eudemis porphyrana, E11-14:OAc in a 10:1 mixture with E11-14:OH for Dichrorampha petiverella and Cochylis dubitana), for two species of Gelechiidae (Z9-14:OAc in a mixture with either Z10-14:OAc in a ratio 1:1, E9-14:OAc in a ratio 1:10 or E10-14:OAc in a ratio 10:1 for Bryotropha galbanella, Z10-14:OAc and E9-14:OAc in a ratio 10:1 for B. mundella), as well as for one species of each of the families Yponomeutidae (Z7-14:OAc for Paraswammerdamia lutarea) and Oecophoridae (Z10-14:OAc and E9-14:OAc in a ratio 10:1 for Pseudatemelia josephinae). Preliminary composition of sex attractants was established for three moth species of the family Gracillariidae (Z10-14:OAc in a 1:10 mixture with E9-14:OAc for Phyllonorycter heegerella, Ph. coryli and Ph. dubitella) and for one species of the family Gelechiidae (Z9-14:OAc for Bryotropha terella). Inhibitors of the sex attractants were found for four leafminer species of the family Gracillariidae (Z7-, Z9- and Z10-12:OAc for Phyllonorycter sorbi, Z10-, E10-12:OH and E10-14:OH for Ph. mespilella, E10-12:OH for Ph. cydoniella, Z10-12:OH and E10-14:OH for Ph. oxyacanthae), for three species of Tortricidae (E9-, Z11- and E11-14:OAc for Endothenia ericetana, E11-14:OAc for Gypsonoma minutana, E10- and E11-14:OAc for Epagoge grotiana), and for one species from the family Pyralidae (Z10-, E10- and E11-14:OAc for Pyrausta aurata). Data from male behavior tests in tube olfactometers are presented for Phyllonorycter blancardella, Ph. sorbi, Ph. dubitella and Ph. strigulatella and active compounds revealed.

Journal of Applied Entomology published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C14H26O2, HPLC of Formula: 16974-11-1.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Page, Philip C. Bulman published the artcileBinaphthalene-Derived Iminium Salt Catalysts for Highly Enantioselective Asymmetric Epoxidation, Application In Synthesis of 126613-06-7, the publication is European Journal of Organic Chemistry (2009), 3413-3426, database is CAplus.

Enantiomerically enriched epoxides are useful intermediates that have found many applications in asym. synthesis, and development of efficient catalysts for asym. epoxidation has received considerable attention. In this manuscript we describe the design, preparation, and use of new highly selective iminium salt organocatalysts, e.g. I, for asym. epoxidation, based around a chiral binaphthalene motif coupled with a chiral substituted dioxane moiety. The new catalysts have been tested in the catalytic asym. epoxidation of unfunctionalized alkenes, and provide up to 95 % ee. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009).

European Journal of Organic Chemistry published new progress about 126613-06-7. 126613-06-7 belongs to esters-buliding-blocks, auxiliary class Chiral Diphenols, name is (R)-[1,1′-Binaphthalene]-2,2′-diyl bis(trifluoromethanesulfonate), and the molecular formula is C22H12F6O6S2, Application In Synthesis of 126613-06-7.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Bulman Page, Philip C. published the artcileIminium salt catalysts for asymmetric epoxidation: the first high enantioselectivities, Quality Control of 126613-06-7, the publication is Organic Letters (2004), 6(10), 1543-1546, database is CAplus and MEDLINE.

A highly enantioselective iminium salt catalyst has been prepared and tested in the catalytic asym. epoxidation of unfunctionalized alkenes, giving up to 95% ee, the highest ee yet reported for iminium salt-catalyzed epoxidation Catalyst loadings as low as 0.1 mol % may be used.

Organic Letters published new progress about 126613-06-7. 126613-06-7 belongs to esters-buliding-blocks, auxiliary class Chiral Diphenols, name is (R)-[1,1′-Binaphthalene]-2,2′-diyl bis(trifluoromethanesulfonate), and the molecular formula is C22H12F6O6S2, Quality Control of 126613-06-7.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics