Ye, Chen-Xi published the artcileAtroposelective Synthesis of Axially Chiral N-Arylpyrroles by Chiral-at-Rhodium Catalysis, Computed Properties of 30414-53-0, the publication is Angewandte Chemie, International Edition (2020), 59(32), 13552-13556, database is CAplus and MEDLINE.
A transformation of fluxional into configurationally stable axially chiral N-arylpyrroles was achieved with a highly atroposelective electrophilic aromatic substitution catalyzed by a chiral-at-metal rhodium Lewis acid. Specifically, N-arylpyrroles were alkylated with N-acryloyl-1H-pyrazole electrophiles in up to 93% yield and with up to >99.5% ee, and follow-up conversions reveal the synthetic utility of this new method [e.g., I + N-acryloyl-1H-pyrazole â?II (up to 93% yield, 92% isolated, 99% ee)]. DFT calculations elucidate the origins of the observed excellent atroposelectivity.
Angewandte Chemie, International Edition published new progress about 30414-53-0. 30414-53-0 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ketone,Ester, name is Methyl 3-oxovalerate, and the molecular formula is C6H8O6, Computed Properties of 30414-53-0.
Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics