Shou, Yufeng published the artcileToward Renewable and Functional Biomedical Polymers with Tunable Degradation Rates Based on Itaconic Acid and 1,8-Octanediol, Application In Synthesis of 617-52-7, the publication is ACS Applied Polymer Materials (2021), 3(4), 1943-1955, database is CAplus.
Biomedical polymers face rigid requirements for the biocompatibility of their monomers, the final polymeric product, and their residual reagents from their synthesis schemes. However, their preparation still heavily relies on nonrenewable resources. Itaconate (ITA) is an organic acid that is used as a platform chem. for the production of numerous value-added chems. and serves as a valuable green chem. alternative to petrochem. derivatives In recent years, the multiple roles of this mol. in cell metabolism have generated great attention, particularly as a modulator of inflammation and infection. Recently, we developed a family of ITA polyesters that leverage hydrolytically driven degradation to recapitulate its biofunctionality. This renewable-based material platform warrants characterization of material properties based on synthesis conditions in order to advance their potential application. In this work, we describe the development of ITA polyesters relying on defined reaction feed ratios and reaction times. Material characterization highlighted the significant impact of changing molar feed on mol. weight, which corresponded to increased viscosity and decreased percent degradation Using 20% excess ITA monomers in the reaction led to optimal outcomes, suggesting opportunities in future material design. Leveraging this characterization, ITA polyesters can be altered through synthesis conditions to achieve appropriate and specific biopolymer applications.
ACS Applied Polymer Materials published new progress about 617-52-7. 617-52-7 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Aliphatic hydrocarbon chain,Ester, name is Dimethyl itaconate, and the molecular formula is C4H11NO, Application In Synthesis of 617-52-7.
Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics