Sabatini, Stefano published the artcile8-Methyl-7-substituted-1,6-naphthyridine-3-carboxylic acids as new 6-desfluoroquinolone antibacterials, Recommanded Product: Ethyl 3-(dimethylamino)acrylate, the publication is Journal of Heterocyclic Chemistry (1999), 36(4), 953-957, database is CAplus.
1,6-Naphthyridine-8-methyl-7-substituted-3-carboxylic acids I (R = N-methylpiperazine, piperidine, 1,2,3,4-tetrahydroisoquinoline) were synthesized as new 6-desfluoroquinolone antibacterials in which the usual fluorine atom at C-6 position was replaced by an endocyclic nitrogen atom. The antibacterial activity of I proved less when compared to our previous 6-amino and 6-hydrogen counterparts. However, the presence of Me group at C-8 position provided good Gram-pos. antibacterial activity, with min. inhibitory concentration values on the same order of ciprofloxacin for the piperidinyl and tetrahydroisoquinolinyl derivatives
Journal of Heterocyclic Chemistry published new progress about 924-99-2. 924-99-2 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Amine,Aliphatic hydrocarbon chain,Ester, name is Ethyl 3-(dimethylamino)acrylate, and the molecular formula is C7H13NO2, Recommanded Product: Ethyl 3-(dimethylamino)acrylate.
Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics