Validation results and analysis of microorganism limit test method for 14 kinds of chemical drugs was written by Li, Hui-e;Zhang, Dan;You, Ya-ning;Zhou, Zhi-yun;Cui, Yu-jin. And the article was included in Xibei Yaoxue Zazhi in 2007.Formula: C17H15NO5 The following contents are mentioned in the article:
The objective is to establish the determination method for the microbial limit of 14 chem. agents. The recovery rate is tested by artificial pollution by 4 exptl. strains to verify whether the bacteriostatic effect is presented. The results show that the recovery rate of the 3 test sample of Letosteine granule (25.50 mg/pack) and nimodipine tablet (group I) are all higher than 70%, and without bacteriostatic effect; the Lufenweima slow release tablet, loratadine orally disintegrating tablets, Letosteine capsule (25.50 mg/capsule) 4 test samples (group II) has certain bacteriostatic effect; while Lexapro tablet, Nifedipine slow release capsule, culvfensuan tablet, famotidine orally disintegrating tablets, Zolpidem Tartrate orally disintegrating tablets (5.10 mg/tablet) and Benorilate tablet, these 7 test samples (group III) has strong bacteriostatic effect. Determination of the microbial limit of test samples in group I is conducted by routine method. Determination of the microbial limit of test samples in group II is conducted by media dilution method (0.2 mL/plate, which is 1 mL for 5 plates). Determination of the microbial limit of test samples in group III is conducted by the membrane filtration with centrifugation method. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Formula: C17H15NO5).
4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Formula: C17H15NO5
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics