Antimicrobial Formulation of Chrysopogon zizanioides Essential Oil in an Emulsified Lotion for Acne was written by Kurrimboccus, Fadilah;Orchard, Ane;Danckwerts, Michael Paul;van Vuuren, Sandy. And the article was included in Planta Medica in 2022.SDS of cas: 31566-31-1 The following contents are mentioned in the article:
Acne is a skin condition arising from excess sebum production and microbial overgrowth within the pilosebaceous unit. Several com. essential oils have shown promising activity against acne-related pathogens. Due to their volatility and thermal instability, the formulation of essential oils into com. products remains a pharmaceutical challenge. Thus, this study aimed to develop a viable anti-acne topical treatment as an oil-in-water emulsified lotion to overcome these challenges. Chrysopogon zizanioides(vetiver) displayed noteworthy antimicrobial activity with a mean min. inhibitory concentration of 0.14 mg/mL against Cutibacterium acnes, Staphylococcus aureus, Staphylococcus epidermidis, and Streptococcus pyogenes. Emulsified lotions containing C. zizanioideswere developed through the hydrophilic-lipophilic balance approach. At tested hydrophilic-lipophilic balance values of 8, 9, and 10, C. zizanioidesemulsified lotions displayed maximum stability at hydrophilic-lipophilic balance 9 with a min. change in mean droplet size and polydispersity index of 20.61 and 33.33%, resp., over 84 days. The C. zizanioidesemulsified lotion at optimum hydrophilic-lipophilic balance 9 completely inhibited the growth of C. acnesand killed S. aureus, S. epidermidis, and S. pyogeneswithin 24 h. Addnl., the lotion retained antimicrobial activity against these test micro-organisms over the 84-day stability test period. Thus, the C. zizanioidesemulsified lotion demonstrated phys. stability and antimicrobial efficiency, making it an ideal natural product anti-acne treatment. This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1SDS of cas: 31566-31-1).
Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.SDS of cas: 31566-31-1
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