Furber, Mark’s team published research in Bioorganic & Medicinal Chemistry Letters in 22 | CAS: 115314-17-5

Bioorganic & Medicinal Chemistry Letters published new progress about 115314-17-5. 115314-17-5 belongs to esters-buliding-blocks, auxiliary class Epoxides,Chiral,Nitro Compound,Sulfonate,Benzene, name is (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate, and the molecular formula is C9H9NO6S, Safety of (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate.

Furber, Mark published the artcileDiscovery and evolution of phenoxypiperidine hydroxyamide dual CCR3/H1 antagonists. Part I, Safety of (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate, the publication is Bioorganic & Medicinal Chemistry Letters (2012), 22(24), 7702-7706, database is CAplus and MEDLINE.

The discovery of potent small mol. dual antagonists of the human CCR3 and H1 receptors is described for the treatment of allergic diseases, for example, asthma and allergic rhinitis. Optimizing in vitro potency and metabolic stability, starting from a CCR1 lead compound, led to compound 20 with potent dual CCR3/H1 activity and in vitro metabolic stability.

Bioorganic & Medicinal Chemistry Letters published new progress about 115314-17-5. 115314-17-5 belongs to esters-buliding-blocks, auxiliary class Epoxides,Chiral,Nitro Compound,Sulfonate,Benzene, name is (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate, and the molecular formula is C9H9NO6S, Safety of (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics