Aziz, Marya published the artcilePhytochemical, pharmacological, and In-silico molecular docking studies of Strobilanthes glutinosus Nees: An unexplored source of bioactive compounds, Name: Dimethyl adipate, the publication is South African Journal of Botany (2022), 618-627, database is CAplus.
Strobilanthes glutinosus (family: Acanthaceae) is one of the important medicinal plants and the current research work was carried out to assess the phytochem., biol., and in-silico evaluations of different solvent extracts of S. glutinosus. The phytochem. composition was assessed by determining qual. phytochem. testing, total bioactive contents, and GC-MS anal. For biol. evaluation, antioxidant (DPPH and FRAP), antibacterial, and enzyme inhibition (urease) potential were determined The methanol extract was found to contain the highest total phenolic (247.85 mg GAE/g extract), and flavonoid content (71.91 mg QAE/g extract), which can be correlated to the observed higher antioxidant potential of this extract On the contrary, the n-hexane extract presented maximum anti-urease activity with IC50 value of 0.244 mg/mL, whereas, in the case of antibacterial assays, a dose-dependent activity was observed Similarly, the GC-MS investigation of methanol extract and n-hexane fraction revealed the tentative identification of several important classes of secondary metabolites. Furthermore, the main compounds as identified by GC-MS were further studied for in-silico mol. docking studies in order to highlight any interactions between the compounds identified and the urease enzyme. Overall, the present investigation highlighted the studied plant extracts to be considered further for the isolation of bioactive compounds for the pharmaceutical and food industry.
South African Journal of Botany published new progress about 627-93-0. 627-93-0 belongs to esters-buliding-blocks, auxiliary class Ploymers, name is Dimethyl adipate, and the molecular formula is C8H14O4, Name: Dimethyl adipate.
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https://en.wikipedia.org/wiki/Ester,
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