Iron Catalyzed Hydroformylation of Alkenes under Mild Conditions: Evidence of an Fe(II) Catalyzed Process was written by Pandey, Swechchha;Raj, K. Vipin;Shinde, Dinesh R.;Vanka, Kumar;Kashyap, Varchaswal;Kurungot, Sreekumar;Vinod, C. P.;Chikkali, Samir H.. And the article was included in Journal of the American Chemical Society in 2018.Name: Methyl heptanoate The following contents are mentioned in the article:
Earth abundant, first row transition metals offer a cheap and sustainable alternative to the rare and precious metals. However, utilization of first row metals in catalysis requires harsh reaction conditions, suffers from limited activity, and fails to tolerate functional groups. Reported here is a highly efficient iron catalyzed hydroformylation of alkenes under mild conditions. This protocol operates at 10-30 bar syngas pressure below 100 掳C, utilizes readily available ligands, and applies to an array of olefins. Thus, the iron precursor [HFe(CO)4]–[Ph3PNPPh3]+ in the presence of tri-Ph phosphine catalyzes the hydroformylation of 1-hexene, 1-octene, 1-decene, 1-dodecene, 1-octadecene, trimethoxy(vinyl)silane, trimethyl(vinyl)silane, cardanol, 2,3-dihydrofuran, allyl malonic acid, styrene, 4-methylstyrene, 4-iBu-styrene, 4-tBu-styrene, 4-methoxy styrene, 4-acetoxy styrene, 4-bromo styrene, 4-chloro styrene, 4-vinylbenzonitrile, 4-vinylbenzoic acid, and allyl benzene to corresponding aldehydes in good to excellent yields. Both electron donating and electron withdrawing substituents could be tolerated and excellent conversions. Remarkably, the addition of 1 mol % acetic acid promotes the reaction to completion within 16-24 h. Detailed mechanistic investigations revealed in situ formation of an iron-dihydride complex [H2Fe(CO)2(PPh3)2] (A) as an active catalytic species. This finding was further supported by cyclic voltammetry investigations and intermediacy of an Fe(0)-Fe(II) species was established. Combined exptl. and computational investigations support the existence of an iron-dihydride as the catalyst resting state, which then follows a Fe(II) based catalytic cycle to produce aldehyde. This study involved multiple reactions and reactants, such as Methyl heptanoate (cas: 106-73-0Name: Methyl heptanoate).
Methyl heptanoate (cas: 106-73-0) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Name: Methyl heptanoate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics