Phytochemical characterisation of Phlomis linearis Boiss. & Bal and screening for anticholinesterase, antiamylase, antimicrobial, and cytotoxic properties was written by Goger, Gamze;Tukyolu, Ummuhan;Gusen, Ezgi Nur;Yur, Suleyman;Karaduman, Abdullah Burak;Goger, Fatih;Tekin, Mehmet;Ozek, Gulmira. And the article was included in Turkish Journal of Chemistry in 2021.Computed Properties of C20H40O2 The following contents are mentioned in the article:
In the present work, essential oil and fatty acids and extracts obtained from aerial parts of Phlomis linearis Boiss. & Bal. were investigated for chem. composition and biol. activities. The phytochem. analyses were conducted with gas chromatographymass spectrometry/flame ionisation detector (GC-MS/FID) and liquid chromatog.-mass spectromtetry (LC-MS/MS) techniques. The extracts and essential oil were studied for 伪-amylase and acetylcholinesterase activities with two different spectrophotometric methods. Antimicrobial activities of the extracts were investigated by microdilution. The extracts were evaluated in vitro for cytotoxic effects against cancer and normal cell lines by MTT assay. The essential oil (EO) contained 伪-pinene (12.5%) and 尾-caryophyllene (10.7%) as main compounds Palmitic (26.5%) and nonadecanoic acids (26.6%) were determined as fatty acids. Phytochem. anal. of the extracts found phenolic acids, phlinosides, verbascoside, and flavonoids. The extracts and essential oil demonstrated poor 伪-amylase inhibitory activity. The best acetylcholinesterase inhibitory activity was obtained for diethly ether extract of P. linearis (67.2 卤 3.4%) at 10 mg /mL concentration Et acetate extract found to be effective against Staphlococcus aureus at a min. inhibitory concentration (MIC) of 156.26 渭g/mL. Di-Et ether extract of P. linearis was active on A549 cell lines with an IC50 = 316 卤 4.16 渭g/mL when compared with cisplatin IC50 = 24.43卤 0.14 渭g/mL. To the best of our knowledge, the present work is the first comprehensive report on anti-acetylcholinesterase, anti-伪-amylase, and antimicrobial activities, as well as cytotoxic effects of P. linearis. This study involved multiple reactions and reactants, such as Methyl nonadecanoate (cas: 1731-94-8Computed Properties of C20H40O2).
Methyl nonadecanoate (cas: 1731-94-8) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Computed Properties of C20H40O2
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics