ãEfficient synthesis of 1-iodoalkynes via Al2O3 mediated reaction of terminal alkynes and N-iodosuccinimideã?was written by Yao, Ming; Zhang, Jingjing; Yang, Sen; Xiong, Hangxing; Li, Li; Liu, E.; Shi, Hong. HPLC of Formula: 623-47-2 And the article was included in RSC Advances in 2020. The article conveys some information:
Iodination of terminal alkynes using N-iodosuccinimide (NIS) in the presence of γ-Al2O3 was developed to afford 1-iodoalkynes RC≡CI [R = CH2CH2OH, Ph, 2-pyridyl, etc.] with good to excellent yields (up to 99%). This described approach featured excellent chemoselectivity, good functional group tolerance and utilization of an inexpensive catalyst. The experimental process involved the reaction of Ethyl propiolate(cas: 623-47-2HPLC of Formula: 623-47-2)
Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.HPLC of Formula: 623-47-2
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics