Yang, Chi; Wu, Tian-Rui; Li, Yan; Wu, Bing-Bing; Jin, Ruo-Xing; Hu, Duo-Duo; Li, Yuan-Bo; Bian, Kang-Jie; Wang, Xi-Sheng published an article in 2021. The article was titled 《Facile synthesis of axially chiral styrene-type carboxylic acids via palladium-catalyzed asymmetric C-H activation》, and you may find the article in Chemical Science.Synthetic Route of C10H10O2 The information in the text is summarized as follows:
A novel method by a one-step introduction of axial chirality and sterically hindered group were developed for facile synthesis of axially chiral styrene-type carboxylic acids. With the palladium-catalyzed C-H arylation and olefination of readily available cinnamic acid established, this transformation demonstrated excellent yield, excellent stereocontrol (up to 99% yield and 99% ee), and broad substrate scope under mild conditions. The axially chiral styrene-type carboxylic acids produced were successfully applied to Cp*Co(III)-catalyzed asym. C-H activation reactions, indicating their potential as chiral ligands or catalysts in asym. synthesis. In the part of experimental materials, we found many familiar compounds, such as Benzyl acrylate(cas: 2495-35-4Synthetic Route of C10H10O2)
Benzyl acrylate(cas: 2495-35-4) is a reagent that can be used in the preparation of 2-(Phosphonomethyl)pentanedioic Acid, a selective glutamate carboxypeptidase 2 (GCP-II) inhibitor. It can also be used in the preparation of high refractive index polyacrylates.Synthetic Route of C10H10O2
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics