Wu, Yinrong; Wen, Kangmei; Chen, Jiewen; Shi, Jie; Yao, Xingang; Tang, Xiaodong published an article in 2021. The article was titled 《Copper-Mediated Decarboxylative Coupling between Arylacetic Acids and 1,3-Dicarbonyl Compounds》, and you may find the article in Organic Letters.Electric Literature of C7H12O3 The information in the text is summarized as follows:
A copper-mediated decarboxylative coupling reaction between arylacetic acids and 1,3-dicarbonyl compounds was described for the synthesis of ((indolyl)methyl)-oxocycloalkyl-esters, e.g., I. Significantly, methanocycloocta[b]indoles II [R = COOEt, CONHEt, SO2Ph, etc.; R1 = H, 4-Cl, 5-Br, etc.] were also obtained by sequential intramol. dehydrocyclization process in some cases. This protocol featured a broad substrate scope, simple operations, and good yields. Moreover, the products exhibited potent antiproliferative activity against the human cancer cell lines by a MTT assay. In the experiment, the researchers used Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3Electric Literature of C7H12O3)
Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. They are most widely used as solvents, especially in industries manufacturing explosives, lacquers, paints, and textiles. Ketones are also used in tanning, as preservatives, and in hydraulic fluids.Electric Literature of C7H12O3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics