In 2008,Snape, Timothy J. published 《α-Arylation of aryl ketones: expanding the scope of the Truce-Smiles rearrangement》.Synlett published the findings.Reference of Methyl 4-fluoro-3-nitrobenzoate The information in the text is summarized as follows:
The Truce-Smiles rearrangement was applied to the synthesis of substituted α-aryl aryl ketones and the synthetic utility of the products was demonstrated by the conversion of one of them to 2-(1H-indol-2-yl)phenol. In addition to this study using Methyl 4-fluoro-3-nitrobenzoate, there are many other studies that have used Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9Reference of Methyl 4-fluoro-3-nitrobenzoate) was used in this study.
Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9) belongs to methyl benzoate. Methyl benzoate reacts at both the ring and the ester, depending on the substrate. Electrophiles attack the ring, illustrated by acid-catalysed nitration with nitric acid to give methyl 3-nitrobenzoate.Reference of Methyl 4-fluoro-3-nitrobenzoateMethyl 4-fluoro-3-nitrobenzoate is used to prepare dimethyl 3-nitro-3′,4-oxydibenzoate by reacting with 3-hydroxy-benzoic acid methyl ester.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics